HPMC E3, E5, E6, E15, E50, E4m, K4m, K100, K100m for Pharma Grade

HPMC, or Hydroxypropyl Methylcellulose, is a commonly used excipient in the pharmaceutical industry. The different grades of HPMC refer to variations in the molecular weight and degree of substitution of the polymer, which can affect its properties and performance in different pharmaceutical applications.

Here is a brief overview of some common HPMC grades and their properties:

• HPMC E3: low molecular weight HPMC with a viscosity of 2.4-3.6 cps. It is commonly used as a binder, disintegrant, and thickener in tablets and capsules.
• HPMC E5: low molecular weight HPMC with a viscosity of 4-6 cps. It is often used as a binder and matrix former in sustained-release tablets and as a thickener in suspensions.
• HPMC E6: low molecular weight HPMC with a viscosity of 4.8-7.2 cps. It is commonly used as a binder and matrix former in sustained-release tablets and as a thickener in suspensions.
• HPMC E15: low molecular weight HPMC with a viscosity of 12-18 cps. It is commonly used as a binder, matrix former, and sustained-release agent in tablets and capsules.
• HPMC E50: low molecular weight HPMC with a viscosity of 40-60 cps. It is commonly used as a matrix former and sustained-release agent in tablets and capsules.
• HPMC E4m: high molecular weight HPMC with a viscosity of 3,000-5,600 cps. It is commonly used as a matrix former and sustained-release agent in tablets and capsules.
• HPMC K4m: high molecular weight HPMC with a viscosity of 3,000-5,600 cps. It is commonly used as a matrix former and sustained-release agent in tablets and capsules.
• HPMC K100: Low molecular weight HPMC with a viscosity of 80-120 cps. It is commonly used as a matrix former and sustained-release agent in tablets and capsules.
• HPMC K100m: very high molecular weight HPMC with a viscosity of 80,000-120,000 cps. It is commonly used as a matrix former and sustained-release agent in tablets and capsules.

The choice of HPMC grade will depend on the specific formulation requirements and performance characteristics needed for the particular pharmaceutical product.