Here is a table outlining some common technical data for hydroxypropyl methylcellulose (HPMC):
Property | Value |
---|---|
Chemical structure | Cellulose derivative |
Molecular formula | (C6H7O2(OH)x-m(OCH3)y-n(OCH2CH3)z)n |
Molecular weight range | 10,000 – 1,500,000 g/mol |
Appearance | White to off-white powder |
Solubility | Soluble in water, insoluble in organic solvents |
Viscosity range | 5 – 100,000 mPa·s (depending on viscosity grade and concentration) |
Gelation temperature range | 50 – 90°C (depending on viscosity grade and concentration) |
pH range | 4.0 – 8.0 (1% solution) |
Moisture content | ≤ 5.0% |
Ash content | ≤ 1.5% |
Heavy metals | ≤ 20 ppm |
Microbial limits | ≤ 1,000 cfu/g for total aerobic microbial count; ≤ 100 cfu/g for total combined yeasts and molds |
Residual solvents | Complies with USP 467 |
Particle size distribution | 90% of particles are within 80 – 250 µm |
Shelf life | 2-3 years when stored in a cool, dry place |
It is important to note that these technical data may vary depending on the specific grade and manufacturer of HPMC. It is always recommended to consult the product specifications provided by the manufacturer for the specific product you are using.